- 5th leading cancer killer in women; most common cause of death from gynecologic malignancies
- Predominantly disease of older white women
- Pregnancy and oral contraceptives decrease risk
- ~10% of tumors in women <45 yr are malignant; ~50% in women >45 yr
- Most common sites of spread: contralateral ovary, peritoneal cavity, pelvic lymph nodes (LNs), para-aortic LNs
- Overall survival: 35% at 5 yr, 28% at 10 yr, 15% at 25 yr
- Prognosis for borderline tumors generally good, even with involvement of the peritoneal cavity