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- Expressionless facies, pill-rolling tremor, rigidity, slowed voluntary movements
- Can be caused by a number of agents, including adverse drug reactions and postencephalitic
PARKINSON'S DISEASE
- Idiopathic form of Parkinsonism
- Prevalence: 1 -2/1000; most common in 50-60 yr old range
- Lewy bodies: round, concentrically laminated, pale eosinophilic cytoplasmic inclusion
- Loss of pigmented neurons from the substantia nigra, with pigment in macrophages and a reactive astrocytosis